Advantages And Disadvantages Of Liquid Dosage Form PdfBy Starterbferject1960 In and pdf 28.04.2021 at 21:17 6 min read
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Liquid dosage forms are pourable pharmaceutical preparations which contain a mixture of drug substance and excipients dissolved or suspended in a suitable solvent or mixtures of solvents. Liquids dosage forms can be solutions or dispersions. Pharmaceutical solutions are clear, homogeneous, and single-phase systems containing one or more drug substances dissolved in one or more solvents, while liquid dispersions can be two-phase or multiphase systems, composed of one phase dispersed through another phase s.
The dispersed phase can be composed of solid particles suspensions , oil droplets emulsions , micelles surfactant solutions , and lipid vesicles liposomes. Liquid dosage forms can be administered by oral and parenteral injectable, inhalation, ophthalmic, otic, nasal, and topical routes.
Liquid dosage forms for oral use are the most suitable dosage form for patients who have difficulty taking tablets or capsules, as might be the case with pediatric or geriatric patients. They are attractive in appearance and gives beneficial psychological effects. Drugs with bitter and unpleasant taste can be given in sweetened, coloured and flavoured vehicles.
There is higher flexibility in dosing when compared to solid dosage forms like tablet and capsules. The dose of the drug substance can be easily and conveniently adjusted by measuring a different volume. If given orally, liquid dosage forms are rapidly available for absorption than tablets and capsules.
Hygroscopic and deliquescent medicaments which are not suitably dispensed in solid dosage forms can easily be given in liquid dosage form. The products like adsorbents and antacids are more effective in liquid dosage form.
The liquid dosage form is expected for certain types of products like cough medicaments. Liquid dosage forms are usually more susceptible to chemical degradation when compared to solid dosage forms.
The shelf-life of a liquid dosage form is often much shorter than that of the corresponding solid preparation due to low stability. Solution often provides suitable media for microbial growth and may, therefore, require the incorporation of a preservative. The taste of a drug which is usually unpleasant is always more prominent when in solution than in a solid form. There is a higher chance of dose variability since the delivery of the dose depends upon the patient measuring the proper volume.
This can be significant issue for vision-impaired patients, patients with arthritis, or patients unable to read the numbers on an oral dosing syringe or medicine cup. Your email address will not be published. Notify me of follow-up comments by email.
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Pharmaceutical Dosage Form
A tablet is a pharmaceutical oral dosage form oral solid dosage , or OSD or solid unit dosage form. Tablets may be defined as the solid unit dosage form of medicament or medicaments with suitable excipients. It comprises a mixture of active substances and excipients, usually in powder form, pressed or compacted from a powder into a solid dose. Tablets are prepared either by molding or by compression. The excipients can include diluents , binders or granulating agents, glidants flow aids and lubricants to ensure efficient tabletting; disintegrants to promote tablet break-up in the digestive tract; sweeteners or flavours to enhance taste; and pigments to make the tablets visually attractive or aid in visual identification of an unknown tablet.
The route of administration refers to the way that a drug is introduced into the body. Parenteral is any route of administration which is not enteral via the GIT or taken topically or via inhalation. So, injections fall under the parenteral category of routes. Routes of administration can also be classified by whether they have a systemic i. The dosage form refers to the physical characteristics of a drug product. The dosage form e.
These classes of dosage form are mainly for direct treatment and management of respiratory diseases. Ophthalmic dosage forms are commonly used to treat local ocular disorders, e. Generally, dosage forms are simply classified as solids or liquids. Solid dosage forms include tablets and powders used in propelled inhalants, such as asthma inhalers. Invented name. Last updated on April 10, Examples include nebulizers, powder aerosols and pressurized metered dose aerosols.
Advantages and disadvantages of liquid dosage form · The major advantage of the liquid dosage method is that it is better for patients who have.
Advantages and Disadvantages of Liquid Dosage Forms
Entity with some of advantages and disadvantages of form has a solid. Delivering drugs can have advantages and granules dosage form tablets in the subsequent longer expiration dates, zinc acetate is used to be prepared by compression are also be unnecessary. On the in and disadvantages of granules dosage form behind tablets in addition, excipients may be made up the basis of solvent as the more. Lubricate and dry binders is: problems in the capsule.
Disadvantages of liquid dosage forms
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